{"id":208,"date":"2014-10-14T05:15:28","date_gmt":"2014-10-14T09:15:28","guid":{"rendered":"https:\/\/intranet.chemservice.com\/news\/2014\/10\/government-report-classifies-4-chemical-compounds-as-carcinogens\/"},"modified":"2018-05-31T16:09:29","modified_gmt":"2018-05-31T20:09:29","slug":"government-report-classifies-4-chemical-compounds-as-carcinogens","status":"publish","type":"post","link":"https:\/\/intranet.chemservice.com\/news\/government-report-classifies-4-chemical-compounds-as-carcinogens\/","title":{"rendered":"Government report classifies 4 chemical compounds as carcinogens"},"content":{"rendered":"<p>The National Cancer Institute estimated that doctors will diagnose more than 1.6 million new cases of cancer in the U.S. in\u00a02014. During this same time period, nearly 586,000 patients will die from these malignant diseases. The most common forms of cancer are prostate cancer, breast cancer, lung cancer, colorectal cancer, melanoma, bladder cancer and non-Hodgkin lymphoma.<\/p>\n<p>Cancer is a complex disease with many potential causes, including hereditary genetic aberrations. However, carcinogens, such as radiation and a wide array of chemical compounds, also elevate individuals&#8217; risk levels. This underscores the importance of warning consumers about what chemical compounds are carcinogenic, how to avoid them and how to protect themselves when exposure is inevitable.<\/p>\n<p>To that end, Congress requires the\u00a0National Toxicology Program to prepare a regular\u00a0Report on Carcinogens for the Secretary of the U.S. Department of Health and Human Services. The most recent report, which is the 13th to be issued, <a href=\"http:\/\/www.niehs.nih.gov\/news\/newsroom\/releases\/2014\/october2\/index.cfm\" target=\"_blank\" rel=\"noopener\">draws attention to four substances in particular<\/a>.<\/p>\n<p>&#8220;Identifying substances in our environment that can make people vulnerable to cancer will help in prevention efforts,&#8221; Linda Birnbaum, Ph.D., director of the National Institute of Environmental Health Sciences and the NTP, said in a statement. &#8220;This report provides a valuable resource for health regulatory and research agencies, and it empowers the public with information people can use to reduce exposure to cancer causing substances.&#8221;<\/p>\n<p>Any chemical compounds listed in the report are designated as known human carcinogens or reasonably anticipated human carcinogens. For the 13th\u00a0Report on Carcinogens, the following four substances have been highlighted:<\/p>\n<p><strong>1. Ortho-toluidine<\/strong><br \/>\nOrtho-toluidine is usually produced internationally and imported into the U.S., where it is used in pesticides, dyes, rubber chemicals and several other products, including medical items.\u00a0Previously, ortho-toluidine was considered a reasonably anticipated human carcinogen since 1983. However, more recent studies made credible links between ortho-toluidine and urinary bladder cancer, prompting the\u00a0NTP\u00a0to reclassify it as a known human carcinogen.<\/p>\n<p>According to the U.S. Centers for Disease Control and Prevention, individuals who work with ortho-toluidine\u00a0must take several cautionary measures to minimize their contact with the substance. Butyl rubber gloves provide the best protection for handling ortho-toluidine. Additionally, workers need to remember to take advantage of workplace showers and surveillance programs, and refrain from taking work clothes home. Respirators that contain\u00a0organic vapor cartridges, approved by the\u00a0National Institute for Occupational Safety and Health, will protect the airways.<\/p>\n<p><strong>2. 1-bromopropane<\/strong><br \/>\n<a href=\"https:\/\/intranet.chemservice.com\/1-bromopropane-n-10029-1g.html\" target=\"_blank\" rel=\"noopener\">1-bromopropane<\/a>\u00a0is a solvent that has been used for aerosol-applied adhesives and aircraft maintenance. It can also clean optics, electronics and metals. Additionally, the U.S. Department of Labor noted that 1-bromopropane can be found in products used for dry cleaning and asphalt production. The NTP designated 1-bromopropane as a reasonably anticipated human carcinogen after laboratory experiments revealed it caused tumors to develop in rodents. No studies have made such a connection among humans.<\/p>\n<p>1-bromopropane\u00a0is more likely to impact workers in various fields rather than individuals in the general population. According to the DOL, there are several short-term health problems associated with this substance. Workers who breathe in its vapors may experience headaches, dizziness, confusion, difficulty walking or talking, loss of muscle control in the limbs or loss of consciousness. The chemical may also irritate the eyes, mucous membranes and skin.<\/p>\n<p><strong>3. Cumene<\/strong><br \/>\n<a href=\"https:\/\/intranet.chemservice.com\/isopropylbenzene-n-12276-1g.html\" target=\"_blank\" rel=\"noopener\">Cumene<\/a> is a natural component of coal tar and petroleum that is also present in tobacco smoke. Different manufacturers will use it in the production of acetone and phenol. Exposure is most likely to occur in places where cumene is produced. Laboratory studies showed that cumene\u00a0may cause tumors to form in the lungs and livers of rodents, but no such human studies exist. Therefore, the NTP designated cumene as a reasonably anticipated human carcinogen.<\/p>\n<p>According to the CDC, there are several devices that can protect workers from inhaling cumene vapors, depending on the level of exposure. These products include respirators with face masks and self-contained breathing apparatuses.<\/p>\n<p><strong>4. Pentachlorophenol and by-products of its synthesis<\/strong><br \/>\nPentachlorophenol\u00a0has been a restricted-use pesticide in the U.S. since the 1980s. The substance also treats lumber and timber used for construction purposes, as well as utility poles, fence posts and wood pilings. Individuals who work with such products are likely to be exposed to pentachlorophenol, but people in the general public may also inhale dust from treated products or contaminated soil. Animal studies of this chemical showed tumors forming in mice, and human studies suggested it raises the risk of non-Hodgkin&#8217;s lymphoma, prompting the NTP to classify it as a reasonably anticipated human carcinogen.<\/p>\n<p>According to the U.S. Environmental Protection Agency, wood-preserving factories need to make sure they do not release this chemical into drinking water sources. The\u00a0maximum contaminant level of pentachlorophenol is 1 part per billion.<\/p>\n<p>The NTP pointed out that exposure to these chemicals will not necessarily in and of itself cause cancer. The level of risk is tied to amount and duration of exposure, as well as individuals&#8217; predisposition to malignant disease.<\/p>\n<p><script>(function(w,pk){var s=w.createElement('script');s.type='text\/javascript';s.async=true;s.src='\/\/pumpkin.brafton.com\/pumpkin.js';var f=w.getElementsByTagName('script')[0];f.parentNode.insertBefore(s,f);if(!pk.__S){window._pk=pk;pk.__S = 1.1;}pk.host='conversion.brafton.com';pk.clientId='0';})(document,window._pk||[])<\/script><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Congress requires the National Toxicology Program to prepare a regular Report on Carcinogens for the Secretary of the U.S. Department of Health and Human Services.<\/p>\n","protected":false},"author":1,"featured_media":209,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":[],"categories":[51],"tags":[],"_links":{"self":[{"href":"https:\/\/intranet.chemservice.com\/news\/wp-json\/wp\/v2\/posts\/208"}],"collection":[{"href":"https:\/\/intranet.chemservice.com\/news\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/intranet.chemservice.com\/news\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/intranet.chemservice.com\/news\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/intranet.chemservice.com\/news\/wp-json\/wp\/v2\/comments?post=208"}],"version-history":[{"count":2,"href":"https:\/\/intranet.chemservice.com\/news\/wp-json\/wp\/v2\/posts\/208\/revisions"}],"predecessor-version":[{"id":670,"href":"https:\/\/intranet.chemservice.com\/news\/wp-json\/wp\/v2\/posts\/208\/revisions\/670"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/intranet.chemservice.com\/news\/wp-json\/wp\/v2\/media\/209"}],"wp:attachment":[{"href":"https:\/\/intranet.chemservice.com\/news\/wp-json\/wp\/v2\/media?parent=208"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/intranet.chemservice.com\/news\/wp-json\/wp\/v2\/categories?post=208"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/intranet.chemservice.com\/news\/wp-json\/wp\/v2\/tags?post=208"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}